HK1 Antilichaam / Hexokinase 1

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.

Immunohistochemistry (FFPE) : 1-2 µg/mL, Western blot: 2-4 µg/mL

P19367

Human

A portion of amino acids 1-200 from human Hexokinase 1 protein was used as the immunogen for the HK1 antibody.

HK1/9509

IHC-P, WB

Protein G affinity

Purified

This HK1 antibody is available for research use only.

Aliquot the HK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Optimal dilution of the HK1 antibody should be determined by the researcher.

Western blot testing of human brain tissue lysate with HK1 antibody (clone HK1/9509) . Predicted molecular weight ~120 kDa.