HL2-m5
Gecertificeerd

HL2-m5

Catalog #: TP3102-01
Maat: 10 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

CAS Number

2130846-15-8

Target

Hedgehog/Smoothened

Related Pathways

GPCR/G Protein, Stem Cells

Bioactivity

HL2-m5 is an inhibitor of the sonic hedgehog/patched (Shh/PTCH1) interaction, with a Kd for Shh of 170 nM. It effectively inhibits the activation of the Hedgehog signaling pathway and the transcription of Gli-controlled genes, with an IC50 of 230 nM.

Smiles

C([C@@H](C(N[C@H]1CC=2C=CC(=CC2)OCCSC[C@@H](C(N[C@H](C(N[C@@H](CC(O)=O)C(N)=O)=O)[C@@H](C)O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC1=O)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC(C)=O)[C@@H](C)O)=O)CC(C)C)=O)CO)=O)C=3C=4C(NC3)=CC=CC4

Molecular Formula

C70H101N15O24S3

Molecular Weight

1632.83

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Beschrijving

HL2-m5 Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamHL2-m5
Categorie
Beschikbare grootte10 mg
CatalogusnummerTP3102-01