HLM006474
Gecertificeerd

HLM006474

Catalog #: C13822-01
Maat: 5 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100

Technische Specificaties

CAS Number

353519-63-8

SKU

C13822-5mg

Target

CDK

Applications

Cell Cycle

Smiles

CCOC1=C (C=C (C=C1) C (C2=C (C3=C (C=CC (=N3) C) C=C2) O) NC4=CC=CC=N4) C

Molecular Formula

C25H25N3O2

Additionnal Information

HLM006474 is a small molecule pan-E2F inhibitor that inhibits DNA binding to E2F4 with IC50 of 29.8 μM in A375 cells. HLM006474 induces a reduction in cell proliferation and an increase in apoptosis. The CDK/Rb/E2F pathway is commonly disrupted in lung cancer, and HLM006474 is shown to have efficacy in lung cancer.

Storage Conditions

3 years -20°C powder

Beschrijving

HLM006474 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamHLM006474
Categorie
Beschikbare grootte5 mg
CatalogusnummerC13822-01