HMBS Mouse Monoclonal Antibody [Kloon ID: UMLBI144]

This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) HMBS mouse monoclonal antibody, clone UMLBI144

PBG-D; PBGD; PORC; UPS

Homo sapiens hydroxymethylbilane synthase (HMBS), transcript variant 1, mRNA.

3145

P08397

Unconjugated

Metabolic pathways, Porphyrin and chlorophyll metabolism

Metabolic pathways, Porphyrin and chlorophyll metabolism

WB 1:2000, IHC 1:200

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

HMBS

https://www.ncbi.nlm.nih.gov/gene/?term=3145

https://www.uniprot.org/uniprot/P08397