HMGA2 (NM 003483) Humaan Recombinant Proteïne

This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Purified recombinant protein of Human high mobility group AT-hook 2 (HMGA2), transcript variant 1, full length, with N-terminal His-Trx tag, expressed in E. coli, 50ug

BABL; HMGI-C; HMGIC; LIPO; SRS5; STQTL9

8091

P52926

NM_003483

12q14.3

E. coli

N-His-Trx

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol.

Druggable Genome

32.1 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

HMGA2

Human

NP_003474

https://www.ncbi.nlm.nih.gov/gene/8091

https://www.uniprot.org/uniprot/P52926

https://www.ncbi.nlm.nih.gov/nuccore/NM_003483

https://www.ncbi.nlm.nih.gov/nuccore/NP_003474