HNF4A Antilichaam

The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.

3172

P41235

Human, Mouse

A synthetic peptide corresponding to a sequence within amino acids 200-300 of human HNF4A (NP_000448.3) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Signal Transduction, Stem Cell, Transcription

Affinity purification

Mouse liver

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 57kDa

IgG

HNF4A

Hepatocyte nuclear factor 4, alpha

Homo sapiens

HNF4A, TCF, HNF4, MODY, MODY1, NR2A1, TCF14, HNF4a7, HNF4a8, HNF4a9, NR2A21, HNF4alpha

WB, IF

Liquid