HNMT Antilichaam

In mammals, histamine is metabolized by two major pathways: N (tau) -methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N (tau) -methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

3176

P50135

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 1-292 of human HNMT (NP_008826.1) .

Unconjugated

Primary Antibodies

Neuroscience

Affinity purification

HT-29

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 33kDa

IgG

HNMT

HepG2

HeLa

Mouse liver

Mouse kidney

Mouse brain

Histamine N-methyltransferase

Homo sapiens

Histamine N-methyltransferase, HMT, HNMT

WB, IHC, IP

Liquid