HNRC Antibody - N-terminal regio : FITC (ARP41037_P050-FITC)

Heterogeneous nuclear ribonucleoprotein C (C1/C2)

C1, C2, HNRNP, HNRPC, SNRPC

3183

P07910

NP_112604

Human, Mouse, Rat, Dog, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human HNRPC

HNRPC belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein can act as a tetramer and is involved in the assembly of 40S hnRNP particles.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has one RRM domain that binds to RNAs. Two alternatively spliced transcript variants have been described for this gene.

SUMO1P1; RALYL; RBM41; ZFYVE26; SUMO1; UBE2I; UBC; SDCBP; LMO2; KPNA4; KPNA3; KPNA2; HNRNPC; EPS8; BRIP1; PALB2; BRCA2; BRCA1; BARD1; CEP250; SUMO2; SUMO3; RAD51; IVNS1ABP; STAU1; MDM2; ERG; EED; RNF2; rev; CDKN2A; PARK2; SRPK2; SRPK1; CLK3; TARDBP; YWHAQ

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

HNRNPC is strongly supported by BioGPS gene expression data to be expressed in Jurkat

0.5 mg/ml

Dog: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

33kDa

Rual, J.F., (2005) Nature 437 (7062), 1173-1178

Wet Ice

303

HNRNPC

HNRNPC

Rabbit

Heterogeneous nuclear ribonucleoproteins C1/C2

NM_031314

LDINLAAEPKVNRGKAGVKRSAAEMYGSVTEHPSPSPLLSSSFDLDYDFQ