HnRNP R Antilichaam / HNRNPR

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs and also contains a nuclear localization motif. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].

Western blot: 1:1000, Immunohistochemistry (FFPE) : 1:50-1:100, Flow cytometry: 1:25 (1x10e6 cells), Immunofluorescence: 1:25

O43390

Human

A portion of amino acids 95-123 from the human protein were used as the immunogen for the hnRNP R antibody.

WB, IHC-P, FACS, IF

Antigen affinity purified

Purified

This hnRNP R antibody is available for research use only.

Aliquot the hnRNP R antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

In 1X PBS, pH 7.4, with 0.09% sodium azide

The stated application concentrations are suggested starting points. Titration of the hnRNP R antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Nuclear, cytoplasmic

Western blot testing of human 1) 293T, 2) A431, 3) A549, 4) HepG2, 5) MOLT4 and 6) U-251 MG cell lysate with hnRNP R antibody. Predicted molecular weight: 67, 71 kDa.