![HNRNPC Recombinant antilichaam [9G1] (OACA12141)](/_ipx/q_80/productPlaceholder.webp)
HNRNPC Recombinant antilichaam [9G1] (OACA12141)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Heterogeneous nuclear ribonucleoprotein C
C1; C2; heterogeneous nuclear ribonucleoprotein C (C1/C2) ; heterogeneous nuclear ribonucleoproteins C1/C2; HNRNP; hnRNP C1/C2; HNRPC; nuclear ribonucleoprotein particle C1 protein; nuclear ribonucleoprotein particle C2 protein; SNRPC.
3183
Human
A synthesized peptide derived from human HNRNPC
• Recombinant Monoclonal
Unconjugated
Recombinant Monoclonal Antibody
Affinity Purified
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles (PubMed:8264621) . Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules (PubMed:12509468, PubMed:16010978, PubMed:7567451, PubMed:8264621) . Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides (PubMed:8264621) . May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm (6) A-switch', facilitating binding of HNRNPC, leading to regulation of mRNA splicing (PubMed:25719671) .
Liquid
-20°C or -80°C
HNRNPC
Heterogeneous nuclear ribonucleoproteins C1/C2
HNRNPC
Beschrijving
HNRNPC Recombinant antilichaam [9G1] (OACA12141) Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
Specificaties
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PIN, FLOATING, TUBE, Stainless Steel, Hydrophobic Coated, 300nL-Slot, 0.787mm Diameter, 17mm Exposed Length, 38.1mm Total Length
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1 Each