HNRNPU Antilichaam - C-terminaal gebied: Biotine (ARP40518_P050-Biotine)

Heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)

SAFA, DEE54, HNRPU, SAF-A, U21.1, pp120, EIEE54, GRIP120, hnRNP U, HNRNPU-AS1

3192

Q00839

NP_114032

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human HNRNPU

HNRNPU belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. HNRNPU contains a RNA binding domain and scaffold-associated region (SAR) -specific bipartite DNA-binding domain. This protein is also thought to be involved in the packaging of hnRNA into large ribonucleoprotein complexes. During apoptosis, this protein is cleaved in a caspase-dependent way. But this cleavage does not affect the function of the encoded protein in RNA metabolism.

FBXW11; FUS; HUWE1; BTRC; UBC; TUBG1; TP53; AURKA; MAGED2; TUBGCP3; CEP57; AURKB; SUMO2; SUMO3; CEP70; CEP76; MDM2; LGALS3BP; EMD; HAUS2; TUBGCP4; CEP250; NEDD1; STAU1; IVNS1ABP; LGR4; ERG; RPA3; RPA2; RPA1; WWOX; RNF2; SHFM1; EED; rev; RPS29; RPS27; RPS6

Biotin

Polyclonal Antibody

WB

Affinity Purified

HNRNPU is strongly supported by BioGPS gene expression data to be expressed in ACHN

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

90kDa

Wet Ice

825

HNRNPU

HNRNPU

Rabbit

Heterogeneous nuclear ribonucleoprotein U

NM_031844

EITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQF