HNRPA0 Antilichaam - middengebied: Biotine (ARP40686 T100-Biotine)

Heterogeneous nuclear ribonucleoprotein A0

HNRPA0

10949

Q13151

NP_006796

Human, Cow, Dog, Pig

The immunogen is a synthetic peptide directed towards the middle region of human HNRPA0

HNRPA0 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind RNAs, followed by a glycine-rich C-terminus.This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind RNAs, followed by a glycine-rich C-terminus.

UBC; SUMO2; SUMO3; STAU1; RPA3; RPA2; RPA1; EED; RNF2; DYNC1LI1; PSMD13; PSMD12; PSMD8; MAP2; DYNC1I2; DHX9; ABCF1; RPS27; TARDBP; CSF2; NPM1; LMNA; AICDA; MAPKAPK2; GADD45A; U2AF2; VCAM1; SRSF1; NKX3-1; MTNR1A; ITGA4; IL7R; HNRNPK; HNRNPH3; HNRNPH2; HNRN

Biotin

Polyclonal Antibody

IF, IP, WB, IHC

0.5 mg/ml

Cow: 93%; Dog: 93%; Human: 100%; Pig: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

34kDa

Lai, F., (2001) Genomics 71 (2), 235-245

Wet Ice

305

HNRNPA0

HNRNPA0

Rabbit

Heterogeneous nuclear ribonucleoprotein A0

NM_006805

KAAVVKFHPIQGHRVEVKKAVPKEDIYSGGGGGGSRSSRGGRGGRGRGGG