Homoharringtonine
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
A plant alkaloid, originally isolated from the Hainan plum yew, that binds to the large ribosomal subunit A-site, competing with aminoacyl-tRNA amino acid side chains, thereby inhibiting the initial elongation step of protein synthesis.1 It also binds to transcription factors NKRF (NF-κB repressing factor) and SP1, down-regulating the Myc pathway.2,3 Dramatically decreases global DNA 5-hydroxymethylcytosine levels via the SP1/TET1 axis.3 Induces apoptosis in tyrosine kinase inhibitor-resistant NSCLC cells4, and is a clinically useful agent for CML and AML5.
Unconjugated
Pale yellow to off-white solid
-20°C
Beschrijving
Homoharringtonine Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
NH-6
ABC-TC0826
1 Vial
Anti-TAT (Thrombin-antithrombin) Antibody
ABS 014-22-1
1000 µL
Anti-APOE2 mouse monoclonal antibody
TD-AB0132
100 µg
CD35 (CR1) mouse monoclonal antibody, clone J3D3, Azide Free
BM2364
0.2 mg
Anti-KIR2DL1 (Rabbit, Monoclonal, Rabbit mAb)
A115392
100 µL
Stains-all
03943-5
5 g
Sudan Blue II;Oil Blue 35
TRC-S688913-500MG
500 mg
Nile Blue A
N8430-01
1 g
Recent gezochte producten
PID antibody
70R-11746
100 ug
PPID antibody
70R-14011
100 ug
PPID antibody
70R-2388
50 ug
PPID Antibody
MBS859079-01
0.1 mg
Canine Distemper Virus Antibody Test (S/P)
VR-CDV-AB-10
10 Tests
Canine Ehrlichia Antibody Test (WB/S/P)
VR-CE-AB-10
10 Tests
Canine Parvovirus Antibody Test (S/P)
VR-CPV-AB-10
10 Tests
PPID antibody
70R-14011
0.1 mg