HOPX/LAGY Polyklonale Antilichaam, FITC-vervoeging

Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity) . May act as a tumor suppressor.

HOD; HOP; OB1; LAGY; TOTO; CAMEO; NECC1; SMAP31; Homeodomain-only protein; Lung cancer-associated Y protein; Not expressed in choriocarcinoma protein 1; Odd homeobox protein 1; HOPX

84525

Q9BPY8

Cytoplasm, Nucleus

Human, Mouse, Rat

21-60/73

HOPX/LAGY

FITC

KLH conjugated synthetic peptide derived from human HOPX/LAGY

IF, Flow-Cyt

Purified by Protein A.

494nm/518nm

1µg/µl

IF (), Flow-Cyt (1ug/Test)

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

84525