HOPX/LAGY Polyklonale Antilichaam, PerCP Vervoeging

Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity) . May act as a tumor suppressor.

HOD; HOP; OB1; LAGY; TOTO; CAMEO; NECC1; SMAP31; Homeodomain-only protein; Lung cancer-associated Y protein; Not expressed in choriocarcinoma protein 1; Odd homeobox protein 1; HOPX

84525

Q9BPY8

Cytoplasm, Nucleus

Human, Mouse, Rat

21-60/73

HOPX/LAGY

PerCP

KLH conjugated synthetic peptide derived from human HOPX/LAGY

IF, Flow-Cyt

Purified by Protein A.

482nm/677nm

1µg/µl

IF (), Flow-Cyt (1ug/Test)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

84525