HP1γ (fosfo Ser93) Antilichaam

At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.

11335;653972

Q13185

NP_009207.2

Human, Mouse, Rat

HP1γ (phospho Ser93) antibody was raised against a peptide sequence around phosphorylation site of Serine 93 (R-L-S (p) -L-S) derived from Human HP1γ .

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

24 kDa

IgG

The antibody detects endogenous levels of HP1γ only when phosphorylated at serine 93.

Western Blot: 1:500~1:1000

CBX3

Chromobox homolog 3

Homo sapiens

Ye Q., J. Biol. Chem. 271:14653-14656 (1996) .

Ye Q., Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.

Koike N., FEBS Lett. 467:17-21 (2000)

HECH, HP1 gamma, HP1Hs-gamma, chromobox 3

WB

15082258

Liquid