HPN536
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
HPN536 is a trispecific, T-cell-activating protein-based construct, which binds to mesothelin-expressing tumor cells, CD3ε on T cells, and to serum albumin. HPN536 specifically redirects T cells for potent redirected lysis of mesothelin-expressing cancer cells with concomitant T-cell activation[1].
12352203
CD3
Immunology/Inflammation
Cancer-programmed cell death
Cancer
99.00
(52.90 kDa)
[1]Molloy ME, et al. Preclinical Characterization of HPN536, a Trispecific, T-Cell-Activating Protein Construct for the Treatment of Mesothelin-Expressing Solid Tumors. Clin Cancer Res. 2021 Mar 1;27 (5) :1452-1462.
Dry Ice
-80°C
http://file.medchemexpress.com/batch_PDF/HY-P991088/HPN536-SDS-MedChemExpress.pdf
Inhibitory Antibodies
Phase 1
Beschrijving
HPN536 is a trispecific, T-cell-activating protein-based construct, which binds to mesothelin-expressing tumor cells, CD3ε on T cells, and to serum albumin. HPN
Specificaties
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