HPRT-antilichaam1F8D11]

The HPRT1 gene provides instructions for making an enzyme called hypoxanthine phosphoribosyltransferase 1. This enzyme allows cells to recycle purines, some of the building blocks of DNA and its chemical cousin RNA.The enzyme hypoxanthine-guanine phosphoribosyltrasferase (E.C.2.4.2.8., HPRT) plays a crucial role in uric acid synthesis and purine metabolism.This enzyme catalyzes the conversion of hypoxanthine and guanine to inosine monophosphate (IMP) and guanosine monophosphate (GMP), respectively, and uses phosphoribosylpyrophosphate (PRPP) as a cosubstrate and as a source of energy . This pathway is also known as the purine salvage pathway because it allows cells to reuse purine compounds to build DNA and RNA.

3251

P00492

P00492

Human

Ni-NTA purified truncated recombinant HPRT expressed in E. Coli strain BL21 (DE3) .

1F8D11

Unconjugated

Primary Antibodies

Other

Batch dependent

None

Blue Ice

HPRT monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG2b

HPRT1

Hypoxanthine phosphoribosyltransferase 1

Homo sapiens

Manjanatha MG, et.al Mutat Res. 2004 Mar 22;547 (1-2) :5-18.

HPRT, Hypoxanthine-guanine phosphoribosyltransferase, HGPRT

ELISA, WB

123497

Liquid