HRH1 Antilichaam

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. It has been associated with multiple processes, including memory and learning, circadian rhythm, and thermoregulation. It is also known to contribute to the pathophysiology of allergic diseases such as atopic dermatitis, asthma, anaphylaxis and allergic rhinitis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

3269

P35367

Human

Recombinant protein of human HRH1

Unconjugated

Primary Antibodies

Cell Cycle, Growth Factors, Immunology, Innate Immunity, Signal Transduction

Affinity purification

Human colon

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 56kDa

IgG

HRH1

Histamine receptor H1

Homo sapiens

HRH1, histamine receptor H1, HGNC:5182, H1-R, hisH1, histamine receptor, subclass H1

WB, IHC

Liquid