HSD17B13 Antilichaam / 17-beta-HSD 13 / SCDR9

17-beta-Hydroxysteroid dehydrogenase type 13 also known as 17-beta-HSD type 13 is an enzyme that in humans is encoded by the HSD17B13 gene. Hydroxysteroid (17-beta) dehydrogenase 13, also designated Short-chain dehydrogenase/reductase 9 (SCDR9), which regulate the availability of steroids within various tissues throughout the body. HSD17B13 is a 300 amino acid secreted protein that is highly expressed in liver and is also detected in ovary, bone marrow, kidney, brain, lung, skeletal muscle, bladder and testis. The gene encoding HSD17B13 maps to chromosome 4, which houses nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells, ELISA: 0.1-0.5 µg/mL

Q7Z5P4

Human, Mouse, Rat

An E.coli-derived human recombinant protein (amino acids R59-K300) was used as the immunogen for the HSD17B13 antibody.

WB, IHC-P, FACS, ELISA

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This HSD17B13 antibody is available for research use only.

After reconstitution, the HSD17B13 Antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the HSD17B13 antibody should be determined by the researcher.

Cytoplasm

IHC staining of FFPE human liver cancer tissue with HSD17B13 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.