HSD17B13 Antilichaam / DHB13 / 7-beta hydroxysteroïde dehydrogenase 13

HSD17B13 protein is an enzyme that plays a key role in the metabolism of steroids and lipids in the body. Specifically, it is involved in the conversion of various hormones and fatty acids, making it a critical player in maintaining metabolic homeostasis. Additionally, studies have shown that mutations or dysregulation of the HSD17B13 gene can lead to impaired lipid metabolism and contribute to the development of liver diseases such as non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease. HSD17B13 protein is a potential therapeutic target for liver diseases.

Western blot: 1:500-1:1000, Immunohistochemistry (FFPE) : 1:250-1:500

Q7Z5P4

Human

A portion of amino acids 81-110 from the human protein was used as the immunogen for this HSD17B13 antibody.

WB, IHC-P

Antigen affinity

Antigen affinity purified

This HSD17B13 antibody is available for research use only.

Aliquot the HSD17B13 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

In 1X PBS, pH 7.4, with 0.09% sodium azide

Titration of the HSD17B13 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Cytoplasm

IHC testing of FFPE human liver tissue with HSD17B13 antibody. HIER: steam section in pH9 EDTA buffer for 20 min and allow to cool prior to staining.