HSD17B8 Antilichaam

In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.

7923

Q92506

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-261 of human HSD17B8 (NP_055049.1) .

Unconjugated

Primary Antibodies

Cell Cycle, Growth Factors, Neuroscience, Signal Transduction

Affinity purification

HepG2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 27kDa

IgG

HSD17B8

BxPC-3

U-87MG

HeLa

Mouse liver

Mouse pancreas

Hydroxysteroid 17-beta dehydrogenase 8

Homo sapiens

D6S2245E, FABG, FABGL, H2-KE6, HKE6, KE6, RING2, SDR30C1, dJ1033B10.9, estradiol 17-beta-dehydrogenase 8, 17-beta-HSD 8, 17-beta-hydroxysteroid dehydrogenase 8, 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit, 3-oxoacyl-[acyl-carrier-protein] reductase, KAR alpha subunit, estrogen 17-oxidoreductase, ke-6, protein Ke6, really interesting new gene 2 protein, short chain dehydrogenase/reductase family 30C member 1, testosterone 17-beta-dehydrogenase 8

WB, IHC, IF

Liquid