HSD17B8 Mouse Monoclonal Antibody [Kloon ID: LBI2E12]

In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) HSD17B8 mouse monoclonal antibody, clone LBI2E12

D6S2245E; dJ1033B10.9; FABG; FABGL; H2-KE6; HKE6; KE6; RING2; SDR30C1

Homo sapiens hydroxysteroid 17-beta dehydrogenase 8 (HSD17B8), mRNA.

7923

Q92506

Unconjugated

Androgen and estrogen metabolism, Metabolic pathways

Androgen and estrogen metabolism, Metabolic pathways

WB 1:2000, IHC 1:150

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

HSD17B8

https://www.ncbi.nlm.nih.gov/gene/?term=7923

https://www.uniprot.org/uniprot/Q92506