HSP90AA1 Antilichaam - N-terminaal gebied: Biotine (ARP30184_P050-Biotine)

Heat shock protein 90kDa alpha (cytosolic), class A member 1

EL52, HSPN, LAP2, HSP86, HSPC1, HSPCA, Hsp89, Hsp90, LAP-2, HSP89A, HSP90A, HSP90N, Hsp103, HSPCAL1, HSPCAL4, HEL-S-65p

3320

P07900

NP_001017963

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Sheep

The immunogen is a synthetic peptide directed towards the N terminal region of human HSP90AA1

HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1, an inducible form, and HSP90AB1 (MIM 140572), a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM 606219) .

AHSA1; STUB1; HUWE1; ISG15; RAF1; PTGDS; PTGDR; SIRT1; CDC37; STIP1; HSF1; HIF1A; NR3C1; UBC; PTGES3; FUS; CDC25C; CDK1; SUMO1; STK36; KEAP1; PSMD10; AURKA; SUMO2; SUMO3; MAP3K11; MDM2; LGALS3BP; CEP57; AURKB; CEP76; VHL; TUBG1; TP53; BRCA1; CEP250; AIP

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

HSP90AA1 is strongly supported by BioGPS gene expression data to be expressed in MCF7

0.5 mg/ml

Cow: 92%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 92%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

98kDa

Onuoha, S.C., (2008) J. Mol. Biol. 379 (4), 732-744

Wet Ice

854

HSP90AA1

HSP90AA1

Rabbit

Heat shock protein HSP 90-alpha

NM_001017963

HLYKDLQPFILLRLLMPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIIN