Humaan Adiponectrip30 antilichaam

Human Adiponectin, also referred to as AdipoQ, Acrp30, apm-1 or GBP28, is a secreted protein expressed exclusively in differentiated adipocyte (adipokine) . Adiponectin contains a modular structure comprising an N-terminal collagenous domain followed by a C-terminal globular domain (gAcrp30) . Adiponectin plays a role in various physiological processes such as energy homeostasis and obesity. Plasma levels of adiponectin are reduced in obese humans, and decreased levels are associated with insulin resistance and hyperinsulinemia.

ADIPOQ, ACDC, ACRP30, APM1, GBP28, 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, Adipocyte C1q and collagen domain-containing protein, Adipose most abundant gene transcript 1 protein, Gelatin-binding protein

Human

Human

Recombinant human adiponectin (15-244aa) purified from E. coli

1G12

Unconjugated

ELISA, WB

By protein-G affinity chromatography

1 mg/mL (determined by BCA assay)

Adiponectin, Acrp30, ADIPOQ, ACDC, ACRP30, APM1, GBP28, Adiponectin globular domain, Mouse, Adipocyte, C1q and collagen domain-containing protein, 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, ACRP30, Adipose most abunda, Adiponectin, 30 kDa adipocyte complement related protein, ACRP 30, Adipocyte C1q and collagen domain containing protein, Adipocyte complement related 30 kDa protein, Adipocyte complement related protein of 30 kDa, Adipose most abundant gene transcript 1, APM 1, GBP 28, Gelatin binding protein, AAD0602-10 µg, AAD0602-20 µg, AAD0602-50 µg, AAD0602-100 µg, AAD0602-250 µg, AAD0602-500 µg, AAD0602-1 mg, AAD0602-10, AAD0602-20, AAD0602-50, AAD0602-100, AAD0602-250, AAD0602-500, AAD0602-1

Maeda K. et al., (1996) Biochem Biophys Res Commun. 221:286-9.; ; Berg AH. et al., (2001) Nat Med 7:947-53.; ; Berg AH. et al., (2002) Trends Endocrinol Metab. 13: 84-89.; ; Yamauchi T. et al., (2002) Nat Med. 8:1288-95.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Hormones & Cytokines

NP_004788

Q15848

The recombinant proteins (10ng) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human Adiponectin antibody (1:2000) . Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.; ; Lane 1.: Human Adiponectin full length (15-244aa) ; ; Lane 2.: Mouse Adiponectin globular domain (111-247aa) ;