Humaan BMP-2 antilichaam

BMP-2 (Bone morphogenetic protein 2) is multi-functional growth factors that belong to the transforming growth factor beta (TGF beta) superfamily. It plays an important role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. BMP-2 also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells, and is required for cardiac contractility.

Bone morphogenetic protein 2, BMP-2A

Human

Human

Recombinant human BMP2 (283-396aa) purified from E. coli

AT15B3

Unconjugated

ELISA, WB, ICC/IF

By protein-A affinity chromatography

1 mg/mL (determined by BCA assay)

CD159 antigen-like family member A, Bone Morphogenetic protein-2, Bone morphogenetic Protein 2, BMP-2A, BMP2A, BMP2 (monomer), BMP2, ATGA0281-10 µg, ATGA0281-20 µg, ATGA0281-50 µg, ATGA0281-100 µg, ATGA0281-250 µg, ATGA0281-500 µg, ATGA0281-1 mg, ATGA0281-010, ATGA0281-020, ATGA0281-050, ATGA0281-100, ATGA0281-250, ATGA0281-500, ATGA0281-01M

Chen D., et al. (2004) . Growth factors. 22 (4) :233-41. ; ; Schliephake H., et al. (2005) . Clin Oral Implants Res. 17 (6) :666-72.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Hormones & Cytokines

NP_001191

P12643

The cell lysate (40ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human BMP2 antibody (1:1000) . Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. ; ; Lane 1.: HepG2 cell lysate

ICC/IF analysis of BMP2 in Hep3B cells. The cell was stained with ATGA0281 (1:100) . The secondary antibody (green) was used Alexa Fluor 488.