Humaan CD158i/KIR2DS4 antilichaam

The KIR family consists of transmembrane glycoproteins of the Ig superfamily expressed on human Nk cells and a subset of human T cells which they are involved in recognition of either MHC class I molecules or unknown ligand on target cells and inhibit cytotoxic activities. KIR2DS4 is an activating receptor of KIR family.

Killer cell immunoglobulin like receptor two Ig domains and short cytoplasmic tail 4, Killer cell immunoglobulin-like receptor 2DS4, CD158 antigen-like family member I, Natural killer-associated transcript 8, NKAT-8, P58 natural killer cell receptor clones CL-39/CL-17, p58 NK receptor CL-39/CL-17, KKA3, cl-39

Human

Human

Recombinant human kIR2DS4 (23-223aa) purified from E. coli

5F2

Unconjugated

ELISA, WB

By protein-G affinity chromatography

1 mg/mL (determined by BCA assay)

KIR2DS4, CD158i, AKR0504-10 µg, AKR0504-20 µg, AKR0504-50 µg, AKR0504-100 µg, AKR0504-250 µg, AKR0504-500 µg, AKR0504-1 mg, AKR0504-10, AKR0504-20, AKR0504-50, AKR0504-100, AKR0504-250, AKR0504-500, AKR0504-1

Steffens, U. et al. (1998) Tissue Antigens 51:398-413.; ; Kim, J. et al. (1997) J. Immunol. 159:3875-3882.; ; Wagtmann, N. R., et al. (1995) Immunity 2:439-449.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Immunology

NP_036446

P43632

The recombinant proteins (100ng) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human KIR2DS4 antibody (1:1,000) . Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.; ; Lane 1.: Recombinant human KIR2DL1 protein; ; Lane 2.: Recombinant human KIR2DL3 protein; ; Lane 3.: Recombinant human KIR2DL4 protein; ; Lane 4.: Recombinant human KIR2DS4 protein;