Humaan CTGF/CCN2-antilichaam

CTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN intercellular signaling protein) . CTGF has important roles in many biological processes, including cell adhesion, migration, proliferation, angiogenesis, skeletal development, and tissue wound repair, and is critically involved in fibrotic disease and several forms of cancers.

Connective tissue growth factor, CCN2, NOV2, HCS24, IGFBP8

Human

Human

Recombinant human CTGF (27-349 aa) purified from E. coli

AT18E7

Unconjugated

ELISA, WB, ICC/IF

By protein-A affinity chromatography

1 mg/mL (determined by BCA assay)

CTGF, CCN2, Connective tissue growth factor, CCN2, NOV2, HCS24, IGFBP8, ATGA0468-10 µg, ATGA0468-20 µg, ATGA0468-50 µg, ATGA0468-100 µg, ATGA0468-250 µg, ATGA0468-500 µg, ATGA0468-1 mg, ATGA0468-10, ATGA0468-20, ATGA0468-50, ATGA0468-100, ATGA0468-250, ATGA0468-500, ATGA0468-1

Jun JI., et al. (2011) Nat Rev Drug Discov. 10 (12) : 945-63.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

The antibody has been tested by ELISA, Western blot analysis and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Cardiovascular

NP_001892

P29279

The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CTGF antibody (1:1000) . Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. ; ; Lane 1.: Jurkat cell lysate ; ; Lane 2.: A549 cell lysate ; ; Lane 3.: U87MG cell lysate ; ; Lane 4.: A427 cell lysate

ICC/IF analysis of CTGF in Hep3B cells. The cell was stained with ATGA0468 (1:100) . The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue) . {ATGA0468-IF1b.jpg}