Humaan DJ-1/PARK7 antilichaam

Park7/DJ-1, which is a small 189 amino acid protein, is a ubiquitously expressed protein involved in various cellular processes including spermatogenesis and fertilization, cancer, RNA-binding, androgen-receptor signaling and oxidative stress. Mutations in the Park7/DJ-1 are the cause of autosomal recessive early-onset Parkinson's disease 7 (Park7) .

Parkinson disease protein 7, Parkinsonism associated deglycase, parkinson protein 7, Parkinson disease autosomal recessive early onset 7, Maillard deglycase, Oncogene DJ1, Protein DJ-1, DJ-1, DJ1, GATD2, Protein/nucleic acid deglycase DJ-1

Human

Human

Recombinant human Park7/DJ-1 (1-189 aa) purified from E. coli

1B11

Unconjugated

ELISA, WB

By protein-G affinity chromatography

1 mg/mL (determined by BCA assay)

DJ1, DJ-1, DJ 1, DJ1 protein, GATD2, Maillard deglycase, Oncogene DJ1, PARK7, Parkinson disease autosomal recessive early onset 7, Parkinson disease protein 7, Parkinson disease protein 7 CAP1, parkinson protein 7, Parkinsonism associated deglycase, Protein DJ-1, Protein/nucleic acid deglycase DJ-1, SP22, PARK 7, ADJ0618-10 µg, ADJ0618-20 µg, ADJ0618-50 µg, ADJ0618-100 µg, ADJ0618-250 µg, ADJ0618-500 µg, ADJ0618-1 mg, ADJ0618-010, ADJ0618-020, ADJ0618-050, ADJ0618-100, ADJ0618-250, ADJ0618-500, ADJ0618-01M

Meulener MC. et al (2005) J. Neurochem. 93, 1524-1532.; ; Bonifati V. et al (2003) Science. 299, 256-259.; ; Zhou W. et al (2005) J. Biol. Chem. 280, 43150-43158.; ; Junn E. et al (2005) PNAS. 102, 9691-9696.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Neuroscience

NP_009193

Q99497

The cell lysate of Jurkat was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human Park7/DJ-1 antibody (1:1000) . Protein was visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.