Humaan HOMER1-antilichaam

Homer1 (Homer protein homolog 1) belongs to Homer family of proteins that regulate signal transduction through, and the trafficking of, glutamate receptors, as well as maintain and regulate extracellular glutamate levels in corticolimbic brain regions. The Homer1 is enriched at excitatory synapses and binds group 1 metabotropic glutamate receptors (mGluRs) .

HOMER, Homer protein homolog 1, HOMER1, HOMER1A, HOMER1B, HOMER1C, Neuronal immediate early gene, SYN47, Ves 1

Human

Human

Recombinant human Homer1 (1-354aa) purified from E. coli

AT1F3

Unconjugated

ELISA, WB, ICC/IF

By protein-G affinity chromatography

1 mg/mL (determined by BCA assay)

HOMER, HOMER 1, HOMER 1A, HOMER 1B, HOMER 1C, Homer protein homolog 1, Homer protein homolog1, HOMER1, HOMER1A, HOMER1B, HOMER1C, Neuronal immediate early gene, Neuronal immediate early gene 1, SYN 47, SYN47, Ves 1, Ves1, ATGA0146-10 µg, ATGA0146-20 µg, ATGA0146-50 µg, ATGA0146-100 µg, ATGA0146-250 µg, ATGA0146-500 µg, ATGA0146-1 mg, ATGA0146-010, ATGA0146-020, ATGA0146-050, ATGA0146-100, ATGA0146-250, ATGA0146-500, ATGA0146-01M

Szumlinski KK, et al., (2008) Biochem Pharmacol. 75 (1) :112-33.; ; Roche KW, et al., (1999) J Biol Chem.274 (36) :25953-7.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Cell Cycle

NP_004263

Q86YM7

The tissue lysate (50 µg) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human HOMER1 antibody (1:1000) . Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.; ; Lane 1.: Mouse Brain Tissue lysate

ICC/IF analysis of HOMER1 in U87MG cells. The cell was stained with ATGA0146 (1:100) . The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue) .