Humaan SSR4 antilichaam

SSR4, also called TRAPD, is assumed to be involved in protein secretion. It is located in the Xq28 region, arranged in a compact head-to-head manner with the IDH3G gene. These two genes are driven by a bidirectional promoter located between them, and encode proteins involved in unrelated biochemical pathways located in different compartments of the cell. The nontranscribed intergenic region represents only 133 bp and is embedded in a CpG island. The CpG island functions as a bidirectional promoter to initiate the transcription of both functionally unrelated genes with distinct expression patterns. SSR4 consists of six exons and is approximately 70 kb telomeric to the ALD gene. Although alternative splicing of exon 5 has not been detected in human SSR4, transcript variants missing the region homologous to human exon 5 have been detected in both Xenopus laevis and Mus musculus.

Translocon-associated protein subunit delta, TRAPD

Human

Human

Recombinant human SSR4 (24-144aa) purified from E. coli

AT26G5

Unconjugated

ELISA, WB

By protein-A affinity chromatography

1 mg/mL (determined by BCA assay)

SSR4, ATGA0286-10 µg, ATGA0286-20 µg, ATGA0286-50 µg, ATGA0286-100 µg, ATGA0286-250 µg, ATGA0286-500 µg, ATGA0286-1 mg, ATGA0286-10, ATGA0286-20, ATGA0286-50, ATGA0286-100, ATGA0286-250, ATGA0286-500, ATGA0286-1

Brenner V., et al. (1997) Genomics 44 (1) : 8-14.; ; Holthuis JC., et al. (1996) J Biol Chem 312 (Pt 1) (Pt 1) : 205-13.; ; Entrez Gene: SSR4 signal sequence receptor, delta.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Signal Transduction

NP_006271

P51571

The cell lysate of MCF7 (40ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human SSR4 antibody (1:1000) . Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.