Human GLP1R Full Long Protein (VLP)

GLP-1R (Glucagon-Like Peptide-1 Receptor) is a type of G-protein-coupled receptor (GPCR) that plays a crucial role in metabolic regulation, and its specific ligand is glucagon-like peptide-1 (GLP-1) . The binding of GLP-1 to GLP-1R induces a conformational change in the receptor, subsequently triggering downstream signaling cascades. These cascades further activate adenylyl cyclase, ultimately leading to an increase in intracellular cyclic adenosine monophosphate (cAMP) levels. Studies have demonstrated that GLP-1R can regulate insulin secretion in response to GLP-1 through the aforementioned pathway (By similarity), which is of great significance for maintaining systemic glucose homeostasis.

GLP-1R (Glucagon-Like Peptide-1 Receptor) is a type of G-protein-coupled receptor (GPCR) that plays a crucial role in metabolic regulation, and its specific ligand is glucagon-like peptide-1 (GLP-1) . The binding of GLP-1 to GLP-1R induces a conformational change in the receptor, subsequently triggering downstream signaling cascades. These cascades further activate adenylyl cyclase, ultimately leading to an increase in intracellular cyclic adenosine monophosphate (cAMP) levels. Studies have demonstrated that GLP-1R can regulate insulin secretion in response to GLP-1 through the aforementioned pathway (By similarity), which is of great significance for maintaining systemic glucose homeostasis.

This protein .

Arg 24 - Ser 432

GLP1R

Unconjugated

The product MUST be stored at -70°C or lower upon receipt; -70°C for 12 months under sterile conditions.

1.0 EU per μg

Liquid

PBS, Arginine, pH7.4

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Dry ice

-70°C

100ug*1

HEK293

Human

P43220-1

Trehalose