![Humane Glucagon Receptor Recombinant Antilichaam [hGR-2 F6] (OAAV00291)](/_ipx/q_80/productPlaceholder.webp)
Humane Glucagon Receptor Recombinant Antilichaam [hGR-2 F6] (OAAV00291)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
CD40 ligand
CD154; CD40 antigen ligand; CD40 ligand; CD40L; CD40-L; gp39; hCD40L; HIGM1; IGM; IMD3; T-B cell-activating molecule; T-BAM; T-cell antigen Gp39; TNF-related activation protein; TNFSF5; TRAP; tumor necrosis factor (ligand) superfamily member 5; Tumor necrosis factor ligand superfamily member 5.
959
NP_000065.1
Human
Human CD40L
• Recombinant Monoclonal
Hu5c8 (Ruplizumab)
Recombinant Monoclonal Antibody
Purified
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Cytokine that binds to CD40/TNFRSF5 (PubMed:1280226) . Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (PubMed:8617933) . Induces the activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells. Induces tyrosine phosphorylation of isoform 3 of CD28 (PubMed:15067037) . Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching (By similarity) .
PBS with 0.02% Proclin 300.
Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
IgG, kappa
The antibody binds to CD40L with an IC50 of 0.845 ug/ml.
CD40LG
Rabbit
CD40 ligand
CD40LG
NM_000074.2
Beschrijving
Humane Glucagon Receptor Recombinant Antilichaam [hGR-2 F6] (OAAV00291) Beschikbaar in 200 µg. Bestel eenvoudig online met snelle levering.
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