Humane GPR75-eiwit (VLP) voor volledige lengte

G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.

G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.

This protein .

Asn 2 - Val 540

GPR75

Unconjugated

The product MUST be stored at -70°C or lower upon receipt; -70°C for 12 months under sterile conditions.

1.0 EU per μg

Liquid

PBS, Arginine, pH7.4

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Dry ice

-70°C

250ug*2

HEK293

Human

O95800

Trehalose