HYNIC-UBI29-41

HYNIC-UBI29-41 is composed of a bifunctional chelator HYNIC and an antimicrobial peptide UBI 29-41. HYNIC-UBI29-41 retains the antibacterial properties of UBI 29-41, and exhibits good affinity to Gram-positive and Gram-negative bacteria. HYNIC-UBI29-41 can be used as an imaging agent for bacterial infection detection in mouse models, when labeled with the radioactive element technetium (99mTc) [1].

1186217-15-1

12352209

Bacterial

Anti-infection

COVID-19-immunoregulation

Infection

98.34

OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)=O)NC([C@H](CCC(N)=O)NC([C@H](CCSC)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC(CNC([C@H]([C@H](O)C)NC(C(C=C/2)=CNC2=N/N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

C74H126N34O19S

1828.07

[1]Welling MM, et al., Infection detection in mice using 99mTc-labeled HYNIC and N2S2 chelate conjugated to the antimicrobial peptide UBI 29-41. Nucl Med Biol. 2004 May;31 (4) :503-9.

Blue Ice

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

http://file.medchemexpress.com/batch_PDF/HY-P10913/HYNIC-UBI29-41-SDS-MedChemExpress.pdf

Peptides

No Development Reported