
HypoGel® 400 TRT-OH
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
HypoGel® is a hydrophilic Gel® type resin which combines high capacities with good solvent compatibility. Glycol spacers with n = 5 or 10 EO units separate the reactive sites from the polystyrene matrix and modify the hydrophobic properties of the polystyrene backbone. Due to the spacer effect the functional group shows a higher mobility which results in higher kinetic rates and high resolution NMR spectra from immobilized compounds on the bead. The resin is compatible to a wide range of solvents and in contrast to polystyrene even polar solvents like methanol or ethanol can be used. These resins show high loading and a hydrophilicity between polystyrene and TentaGel®. This very acid sensitive linker is useful for the immobilization of alcohols, amines and carboxylic acids. Before use, the trityl alcohol must be converted to the trityl chloride by treatment with acetyl chloride in DCM. The sensitivity towards acids is very comparable to the 2-chlorotrityl linker. Cleavage is in generally achieved by using either 5 - 50% TFA in DCM (containing 5% triisopropylsilane) or acetic acid. This resin can also be used in Fmoc peptide synthesis. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under these conditions. Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin without racemisation. Due to the bulkiness of the trityl group, diketopiperazine formation is suppressed which make this linker ideal for peptides with C-terminal Pro. In this resin the glycol spacer contains 10 EO units which separate the reactive sites from the polystyrene matrix.
110 - 150 µm
0.4 - 0.6 mmol/g
Beschrijving
HypoGel® is a hydrophilic Gel® type resin which combines high capacities with good solvent compatibility. Glycol spacers with n = 5 or 10 EO units separate the
Specificaties
Recent bekeken producten

Denhardt's Solution (50X)
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Pribolab® Automatic Immunoaffinity Column Purification System
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OneTaq Hot Start 2X Master Mix with GC Buffer
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500 Reactions
Recent gezochte producten

FKBP4, ID (FK506-binding Protein 4, Peptidyl-prolyl cis-trans Isomerase FKBP4, PPIase FKBP4, Rotamase, HSP-binding Immunophilin, HBI, FKBP52 Protein, 52kD FK506-binding Protein, 52kD FKBP, FKBP-52, 59kD Immunophilin, FKBP59, p59 Protein, FKBP-4, FKBP52)
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VDAC3 (Voltage-dependent Anion-selective Channel Protein 3, VDAC-3, hVDAC3, Outer Mitochondrial Membrane Protein Porin 3) (MaxLight 750)
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0.1 mL

Vascular Endothelial Growth Factor A (VEGFA, VEGF-A, VEGF, Vascular Permeability Factor, VPF, MVCD1) (MaxLight 750)
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0.1 mL

Vascular Endothelial Growth Factor B (VEGFB, VEGF-B, VEGF-related Factor, VRF, VEGFL) (MaxLight 750)
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VGFR3 (FLT4, VEGFR3, Vascular endothelial growth factor receptor 3, Fms-like tyrosine kinase 4, Tyrosine-protein kinase receptor FLT4) (MaxLight 750)
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VGLL1 (Transcription Cofactor Vestigial-like Protein 1, VGL1, Vgl-1, Protein TONDU, TDU) (MaxLight 750)
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0.1 mL

VHL (Von Hippel-Lindau Disease Tumor Suppressor, pVHL, Protein G7, HRCA1, RCA1, VHL1) (MaxLight 750)
MBS6236096-01
0.1 mL

Villin-1 (VIL1, VIL, D2S1471) (MaxLight 750)
MBS6236097-01
0.1 mL
