I-BET762
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
I-BET762 is a potent inhibitor of the BET family of bromodomains with no activity at bromodomains BAZ2B, SP140, ATAD2, CREBBO, and PCAF.1,2 IC50’s for H4Ac peptide displacement: BRD2 = 32.5nM, BRD3 = 42.4nM, BRD4 = 36.1nM.1 It was able to suppress proinflammatory proteins by macrophage, block acute inflammation in mice1, and suppressed the inflammatory function of T cells3. Inhibition of BET bromodomains results in downregulation of Myc transcription, an important oncogene.4
Unconjugated
Tan solid
-20°C
Beschrijving
I-BET762 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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