I-TAC (CXCL11)

Human I-TAC (Interferon-inducible T cell alpha chemoacttractant) is an 8.3 kDa protein containing 73 amino acid residues. I-TAC is a novel non-ELR CXC chemokine. It is regulated by Interferon and has potent chemoattractant activity for IL-2 activated T cells, but not for freshly isolated unstimulated T cells, neutrophils, or monocytes.

CXCL11; IP9; H174; IP-9; b-R1; I-TAC; SCYB11; SCYB9B

6373

O14625

NP_005400.1

NM_005409.4

4q21.2

Human

Hamster, Mouse, Rabbit, Human, Monkey

FPMFKRGRCLCIGPGVKAVKVADIEKASIMYPSNNCDKIEVIITLKENKGQRCLNPKSKQARLIIKKVERKNF

< 0.1 ng/µg of protein (< 1EU/µg)

> 98% by SDS-PAGE & HPLC analyses

Determined by its ability to chemoattract IL-2 activated T-cells using a concentration range of 0.1-10.0 ng/ml.

73

Lyophilized

8.3 kDa

E. coli