I-TAC (CXCL11)
Gecertificeerd

I-TAC (CXCL11)

Catalog #: M10-086-L500
Maat: 500 µg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100

Technische Specificaties

Description

I-TAC is a "non-ELR" CXC chemokine that is regulated by interferon and signals through the CXCR3 receptor. I-TAC is chemoattractant for IL-2 activated T cells, but does not affect freshly isolated un-stimulated T cells, neutrophils, or monocytes. Recombinant murine I-TAC is a 9.0 kDa protein containing 79 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines.

Synonyms

CXCL11

NCBI Gene ID

56066

UniProt

Q9JHH5

Accession Number

NP_062367.1

Accession Number mRNA

NM_019494.1

Chromosomal Location

5; 5 E3

Reactivity

Mouse

Cross Reactivity

Human, Mouse, Monkey, Bacteria

Sequence

FLMFKQGRCLCIGPGMKAVKMAEIEKASVIYPSNGCDKVEVIVTMKAHKRQRCLDPRSKQARLIMQAIEKKNFLRRQNM

Endotoxin

< 0.1 ng/µg of protein (< 1EU/µg)

Purity

> 98% by SDS-PAGE & HPLC analyses

Bioactivity

Determined by its ability to chemoattract murine CXCR3 transfected HEK/293 cells using a concentration range of 10.0-100.0 ng/ml.

Length

79

Form

Lyophilized

Molecular Weight

9.0 kDa

Host or Source

E. coli

Beschrijving

I-TAC is a "non-ELR" CXC chemokine that is regulated by interferon and signals through the CXCR3 receptor. I-TAC is chemoattractant for IL-2 activated T cells,

Specificaties

ProductnaamI-TAC (CXCL11)
Categorie
Beschikbare grootte500 µg
CatalogusnummerM10-086-L500