IA-6 Antilichaam

IA-6 Antibody: IA-6, also known as insulinoma-associated 2 or INSM2, is related to IA-1 (INSM1), a zinc-finger factor that is expressed in the developing nervous system. While the exact function of IA-6 is not known, other related insulinoma-associated proteins such as IA-2 are major autoantigens in type 1 diabetes. The homology exhibited by IA-6 to IA-1 has led to speculation that IA-6 may also play a role in the regulation of gene transcription.

84684

Q96T92

AAI30380

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Cancer

IA-6 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1471 - Rat Thymus Tissue Lysate

1 mg/mL

IA-6 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

IA-6 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

INSM2

Insulinoma-associated 2

Homo sapiens

Ota T, Suzuki Y, Nishikawa T, et al. Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat. Genet.2004; 36:40-5.

Wildner H, Gierl MS, Strehle M, et al. Insm (IA-1) is a crucial component of the transcriptional network that controls differentiation of the sympathoadrenal lineage. Dev.2008; 135:473-81.

Trembleau S, Penna G, Grigori S, et al. Early Th1 response in unprimed nonobese diabetic mice to the tyrosine phosphatase-like insulinoma-associated protein 2, an autoantigen in type 1 diabetes. J. Immunol.2000; 165:6748-55.

IA-6 Antibody: IA6, IA-6, mlt1, IA6, Nbla106, Insulinoma-associated protein 2, Zinc finger protein IA-6

ELISA, WB

120659844

Liquid