IARS Antilichaam - Middengebied: FITC (ARP54954 P050-FITC)

Isoleucyl-tRNA synthetase

IRS, IARS, ILRS, ILERS, GRIDHH, PRO0785

3376

P41252

NP_038203

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human IARS

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.

UBC; MDM2; SART3; AURKA; SUMO2; SUMO3; STAU1; LGR4; AIMP2; RPLP0; RPL38; RPL24; RPL23A; RPL18; RPL15; QARS; NMT1; MARS; MAP4; HNRNPA2B1; EPRS; DARS; AIMP1; HNRNPUL2; LARS; RPS27L; IGF2BP3; SYNCRIP; EEF1E1; FBXO6; EGFR; UBD; ITGA4; FN1; METTL18; gag; VCAM1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 85%; Dog: 85%; Guinea Pig: 93%; Horse: 85%; Human: 100%; Mouse: 100%; Rabbit: 92%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

144kDa

Wet Ice

1262

IARS

IARS

Rabbit

Isoleucine--tRNA ligase, cytoplasmic

NM_013417

YEAAKVFGLRSRKLKLFLNETQTQEITEDIPVKTLNMKTVYVSVLPTTAD