ICAM 1 (Ab 512) Antilichaam

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2) . During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

3383

P05362

NP_000192.2

Human, Mouse, Rat

ICAM-1 (Ab-512) antibody was raised against a peptide sequence around aa. 510~514 (K-K-Y-R-L) derived from Human ICAM-1.

Unconjugated

Primary Antibodies

Other

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

92 kDa

This antibody detects endogenous level of total ICAM-1 protein.

Western Blot: 1:500~1:1000

ICAM1

Intercellular adhesion molecule 1

Homo sapiens

Greenwood J, et al. (2003) J Immunol; 171 (4) : 2099-2108. Zhou Z, et al. (2005) Eur J Pharmacol; 513 (1-2) : 1-8. Chen YH, et al. (2001) J Cell Biochem; 82 (3) : 512-521

BB2, CD54, P3.58, ICA1, ICAM1

WB

167466198

Liquid