ICAM-1/CD54 Proteïne, Rhesus makak, Recombinant (hFc)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Intercellular adhesion molecule 1 (ICAM1) is known as CD54. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. The endothelial expression of ICAM-1 is increased in atherosclerotic and transplant-associated atherosclerotic tissue and animal models of atherosclerosis. Additionally, ICAM-1 has been implicated in the progression of autoimmune diseases. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2) . During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.
Ice Packs
-20°C
Beschrijving
ICAM-1/CD54 Proteïne, Rhesus makak, Recombinant (hFc) Beschikbaar in 5 µg. Bestel eenvoudig online met snelle levering.
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