Ichorcumab
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets Thrombin. Ichorcumab binds to exosite 1 on thrombin and inhibits substrate binding but not catalytic activity. The isotype control for Ichorcumab can refer to Human IgG4 kappa, Isotype Control.
2589583-20-8
JNJ-375; JNJ-64179375; JNJ-9375
12352203
Thrombin
Metabolic Enzyme/Protease
Neuroscience-Neuromodulation
Cardiovascular Disease
95.33
[Ichorcumab]
(146.260 kDa)
[1]Weitz JI, et al. Randomized phase 2 trial comparing JNJ-9375, a thrombin-directed antibody, with apixaban for prevention of venous thrombosis. J Thromb Haemost. 2019 Dec;17 (12) :2081-2088.
Dry Ice
-80°C
http://file.medchemexpress.com/batch_PDF/HY-P991065/Ichorcumab-SDS-MedChemExpress.pdf
Inhibitory Antibodies
Phase 2
Beschrijving
Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets Thrombin. Ichorcumab binds to exosite 1 on thrombin and inhibits substrate binding but not cata
Specificaties
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