ICRT5
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
A selective CRT (β-catenin-responsive transcription) inhibitor.1 IC50=18 nM for Wnt responsive STF16 luciferase. Acts via interfering with the β-catenin, TCF4 interaction.1 Displays poor inhibition of cell proliferation in triple-negative breast cancer cells.2 Increases the surface expression of MHCII, CD80 and CD86 on unstimulated dendritic cells (DCs) with no detrimental effects on immune-phenotype of stimulated DCs.3 Modulators of Wnt signaling show great promise in animal models of several cancers.4 Cell permeable.
Unconjugated
Yellow solid
-20°C
Beschrijving
ICRT5 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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