![IDE Mouse Monoclonal Antibody [Kloon ID: LBI4E5]](/_ipx/q_80/productPlaceholder.webp)
IDE Mouse Monoclonal Antibody [Kloon ID: LBI4E5]
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified. [provided by RefSeq, Sep 2009]
Carrier-free (BSA/glycerol-free) IDE mouse monoclonal antibody, clone LBI4E5
INSULYSIN
Homo sapiens insulin degrading enzyme (IDE), transcript variant 1, mRNA.
3416
P14735
Unconjugated
Alzheimer's disease
Alzheimer's disease
WB 1:500
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Druggable Genome, Protease
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
IDE
https://www.ncbi.nlm.nih.gov/gene/?term=3416
https://www.uniprot.org/uniprot/P14735
Beschrijving
IDE Mouse Monoclonal Antibody [Kloon ID: LBI4E5] Beschikbaar in 100 µg. Bestel eenvoudig online met snelle levering.
Specificaties
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