IDH3B Antilichaam

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD (+) as the electron acceptor and the other NADP (+) . Five isocitrate dehydrogenases have been reported: three NAD (+) -dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP (+) -dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD (+) -dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD (+) -dependent isocitrate dehydrogenase. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

3420

O43837

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 35-170 of human IDH3B (NP_008830.2) .

Unconjugated

Primary Antibodies

Cancer, Signal Transduction

Affinity purification

NCI-H460

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 42kDa

IgG

IDH3B

HeLa

293T

Mouse kidney

Mouse heart

Mouse lung

Isocitrate dehydrogenase 3 (NAD+) beta

Homo sapiens

Isocitric dehydrogenase subunit beta, isocitrate dehydrogenase, NAD (+) -specific, mitochondrial, beta subunit, isocitrate dehydrogenase [NAD] subunit beta, NAD+-specific isocitrate dehydrogenase beta, NAD+-specific isocitrate dehydrogenase b subunit, NAD+-specific ICDH, NAD (+) -specific ICDH subunit beta, RP46, MGC903, H-IDHB, FLJ11043, isocitrate dehydrogenase 3 (NAD+) beta, IDH3B

WB, IHC, IF

Liquid