IDH3G Antilichaam

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD (+) as the electron acceptor and the other NADP (+) . Five isocitrate dehydrogenases have been reported: three NAD (+) -dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP (+) -dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD (+) -dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD (+) -dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined.

3421

P51553

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 40-170 of human IDH3G (NP_004126.1) .

Unconjugated

Primary Antibodies

Cancer, Signal Transduction

Affinity purification

U-87MG

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 43kDa

IgG

WB: 1:500 - 1:2000

IDH3G

A-431

HepG2

MCF-7

NIH/3T3

Mouse brain

Isocitrate dehydrogenase 3 (NAD+) gamma

Homo sapiens

Isocitric dehydrogenase subunit gamma, isocitrate dehydrogenase, NAD (+) -specific, mitochondrial, gamma subunit, isocitrate dehydrogenase [NAD] subunit gamma, OTTHUMP00000025988, OTTHUMP00000025987, OTTHUMP00000025984, NAD+-specific ICDH, NAD (+) -specific ICDH subunit gamma, NAD (H) -specific isocitrate dehydrogenase gamma subunit, IDH-gamma, H-IDHG, isocitrate dehydrogenase 3 (NAD+) gamma, IDH3G

WB

Liquid