![IDO1 Recombinant antilichaam [9E5] (OACA12388)](/_ipx/q_80/productPlaceholder.webp)
IDO1 Recombinant antilichaam [9E5] (OACA12388)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Indoleamine 2,3-dioxygenase 1
IDO; IDO-1; INDO; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine 2,3-dioxygenase 1; indoleamine-pyrrole 2,3-dioxygenase.
3620
Human
A synthesized peptide derived from human INDO
• Recombinant Monoclonal
Unconjugated
Recombinant Monoclonal Antibody
Affinity Purified
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway (PubMed:17671174) . Involved in the peripheral immune tolerance, contributing to maintain homeostasis by preventing autoimmunity or immunopathology that would result from uncontrolled and overreacting immune responses (PubMed:25691885) . Tryptophan shortage inhibits T lymphocytes division and accumulation of tryptophan catabolites induces T-cell apoptosis and differentiation of regulatory T-cells (PubMed:25691885) . Acts as a suppressor of anti-tumor immunity (PubMed:23103127, PubMed:25157255, PubMed:14502282, PubMed:25691885) . Limits the growth of intracellular pathogens by depriving tryptophan (PubMed:25691885) . Protects the fetus from maternal immune rejection (PubMed:25691885) .
Liquid
-20°C or -80°C
IDO1
Indoleamine 2,3-dioxygenase 1
IDO1
Beschrijving
IDO1 Recombinant antilichaam [9E5] (OACA12388) Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
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