IdoBR1

IdoBR1 is an orally active amino acid with an amino sugar. idoBR1 can significantly inhibit LPS induced TNF-α production and MAPK signaling pathway. idoBR1 can inhibit bacteria and human sialidase. idoBR1 can inhibit bacterial and human sialidase and reduce the binding of CD44 to hyaluronic acid (HA). idoBR1 can reduce the release of pro-inflammatory factors and promote the generation of anti-inflammatory factors. idoBR1 can be used for research on inflammatory conditions[1].

108428-44-0

12352005

P38 MAPK; TNF Receptor

Apoptosis; MAPK/ERK Pathway

COVID-19-immunoregulation

Inflammation/Immunology

OC([C@H]1[C@H]([C@@H]([C@H](CN1)O)O)O)=O

C6H11NO5

177.16

[1]Nash RJ, et al. Iminosugar idoBR1 Isolated from Cucumber Cucumis sativus Reduces Inflammatory Activity. ACS Omega. 2020 Jun 23;5 (26) :16263-16271.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-204592/

Natural Products

No Development Reported